abstract：BACKGROUND:Bronchiectasis is characterized by abnormal, permanent and irreversible dilatation of the bronchi, usually responsible for daily symptoms and frequent respiratory complications. Many causes have been identified, but only limited data are available concerning the association between bronchiectasis and renal t...

journal_title：BMC pulmonary medicine

authors： Dury S,Colosio C,Etienne I,Anglicheau D,Merieau E,Caillard S,Rivalan J,Thervet E,Essig M,Babinet F,Subra JF,Toubas O,Rieu P,Launois C,Perotin-Collard JM,Lebargy F,Deslée G,Spiesser group.

更新日期：2015-11-07 00:00:00

abstract：BACKGROUND:Very few data exist on the management of community-acquired pneumonia (CAP) in patients admitted to hospitals in the Gulf region. The objectives of this study were to describe treatment patterns for CAP in 38 hospitals in five Gulf countries (United Arab Emirates, Kuwait, Bahrain, Oman, and Qatar) and to com...

journal_title：BMC pulmonary medicine

authors： Mahboub B,Al Zaabi A,Al Ali OM,Ahmed R,Niederman MS,El-Bishbishi R

更新日期：2015-09-30 00:00:00

abstract：BACKGROUND:IL-4 and IL-13 play a critical yet poorly understood role in orchestrating the recruitment and activation of effector cells of the asthmatic response and driving the pathophysiology of allergic asthma. The house dust mite (HDM) sheep asthma model displays many features of the human condition and is an ideal ...

journal_title：BMC pulmonary medicine

authors： Liravi B,Piedrafita D,Nguyen G,Bischof RJ

更新日期：2015-09-11 00:00:00

abstract：BACKGROUND:There is emerging evidence regarding the efficacy of exercise training to improve exercise capacity for individuals with non-small cell lung cancer (NSCLC). Cardiopulmonary exercise testing (CPET) is the gold standard measure of exercise capacity; however this laboratory test has limitations for use in resea...

journal_title：BMC pulmonary medicine

authors： Granger CL,Denehy L,Parry SM,Martin J,Dimitriadis T,Sorohan M,Irving L

更新日期：2015-08-12 00:00:00

abstract：BACKGROUND:Telehealth has the potential to improve asthma management through regular monitoring of lung function and/or asthma symptoms by health professionals in conjunction with feedback to patients. Although the benefits of telehealth for improving asthma management have been extensively studied, the feasibility of ...

journal_title：BMC pulmonary medicine

authors： Zairina E,Abramson MJ,McDonald CF,Li J,Dharmasiri T,Stewart K,Walker SP,Paul E,George J

更新日期：2015-07-31 00:00:00

abstract：BACKGROUND:There are not enough data on the epidemiology of asthma in the Kingdom of Saudi Arabia (KSA). We analyzed data from a national household survey conducted in KSA in 2013 to estimate prevalence, associated risk factors and control measurements of asthma. METHODS:The Saudi Health Interview Survey was a cross-s...

journal_title：BMC pulmonary medicine

authors： Moradi-Lakeh M,El Bcheraoui C,Daoud F,Tuffaha M,Kravitz H,Al Saeedi M,Basulaiman M,Memish ZA,AlMazroa MA,Al Rabeeah AA,Mokdad AH

更新日期：2015-07-28 00:00:00

abstract：BACKGROUND:It has been recognized that despite previous stability some patients with idiopathic pulmonary fibrosis (IPF) experience acute clinical deteriorations called acute exacerbations of idiopathic pulmonary fibrosis (AEX-IPF). We hypothesized that pulmonary infection can be excluded based on clinical and laborato...

journal_title：BMC pulmonary medicine

authors： Petrosyan F,Culver DA,Reddy AJ

更新日期：2015-07-10 00:00:00

abstract：BACKGROUND:Physical training has been shown to improve exercise capabilities in patients with asthma. Most studies focused on children and younger adults. Previously, the maximum program duration was six months. It is not known whether the same results may be obtained with lower intensity programs and sustained for tim...

journal_title：BMC pulmonary medicine

authors： Meyer A,Günther S,Volmer T,Taube K,Baumann HJ

更新日期：2015-05-07 00:00:00

abstract：BACKGROUND:During the pathological destruction of lung tissue, neutrophil elastase (NE) degrades elastin, one of the major constituents of lung parenchyma. However there are no non-invasive methods to quantify NE degradation of elastin. We selected specific elastin fragments generated by NE for antibody generation and ...

journal_title：BMC pulmonary medicine

authors： Kristensen JH,Karsdal MA,Sand JM,Willumsen N,Diefenbach C,Svensson B,Hägglund P,Oersnes-Leeming DJ

更新日期：2015-05-03 00:00:00

abstract：BACKGROUND:Neurohumoral activation is present in COPD and might provide a link between pulmonary and systemic effects, especially cardiovascular disease. Because long acting inhaled β-agonists reduce hyperinflation, they could reduce sympathoexcitation by improving the inflation reflex. We aimed to evaluate if inhaled ...

journal_title：BMC pulmonary medicine

authors： Haarmann H,Mohrlang C,Tschiesner U,Rubin DB,Bornemann T,Rüter K,Bonev S,Raupach T,Hasenfuß G,Andreas S

更新日期：2015-04-30 00:00:00

abstract：BACKGROUND:In adults, overweight is associated with reduced lung function, in children evidence on this association is conflicting. We examined the association of body mass index (BMI) and waist circumference (WC) at age 12, and of persistently (at ages 8 and 12 years) high BMI and large WC, with forced vital capacity ...

journal_title：BMC pulmonary medicine

authors： Bekkers MB,Wijga AH,Gehring U,Koppelman GH,de Jongste JC,Smit HA,Brunekreef B

更新日期：2015-04-22 00:00:00

abstract：BACKGROUND:Irisin, a recently discovered myokine, is assumed to be secreted by muscle cells in response to exercise and is involved in the regulation of energy metabolism by browning white adipose tissue cells. However, due to the fact that previous studies revealed conflicting results concerning the association betwee...

journal_title：BMC pulmonary medicine

authors： Kerstholt N,Ewert R,Nauck M,Spielhagen T,Bollmann T,Stubbe B,Felix SB,Wallaschofski H,Gläser S,Friedrich N

更新日期：2015-04-22 00:00:00

abstract：BACKGROUND:Asthma is a common chronic disease among young adults, and several studies have reported increased mortality rates in patients with asthma. However, no study has described sudden unexpected death in a nationwide setting in patients with uncontrolled asthma. We defined uncontrolled asthma as a previous hospit...

journal_title：BMC pulmonary medicine

authors： Gullach AJ,Risgaard B,Lynge TH,Jabbari R,Glinge C,Haunsø S,Backer V,Winkel BG,Tfelt-Hansen J

更新日期：2015-04-14 00:00:00

abstract：BACKGROUND:The Global Lung Function Initiative 2012 (GLI) reference values are currently endorsed by several respiratory societies but evaluations of applicability for adults resident in European countries are lacking. The aim of this study was to evaluate if the GLI reference values are appropriate for an adult Caucas...

journal_title：BMC pulmonary medicine

authors： Backman H,Lindberg A,Sovijärvi A,Larsson K,Lundbäck B,Rönmark E

更新日期：2015-03-25 00:00:00

abstract：BACKGROUND:To evaluate the factors affecting the maximum standardized uptake value (SUVmax) of metastatic lymph nodes in different histological types of non-small cell lung cancer (NSCLC) on integrated positron emission tomography and computed tomography (PET-CT). METHODS:This was a retrospective, single-institution r...

journal_title：BMC pulmonary medicine

authors： Wang Y,Ma S,Dong M,Yao Y,Liu K,Zhou J

更新日期：2015-03-08 00:00:00

abstract：BACKGROUND:Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) has an extremely poor prognosis and there is currently no effective treatment for this condition. Direct hemoperfusion with a polymyxin B-immobilized fiber column (PMX-DHP) improves oxygenation, but it is unclear whether treatment of AE-IPF with PM...

journal_title：BMC pulmonary medicine

authors： Enomoto N,Mikamo M,Oyama Y,Kono M,Hashimoto D,Fujisawa T,Inui N,Nakamura Y,Yasuda H,Kato A,Mimuro S,Doi M,Sato S,Suda T

更新日期：2015-02-22 00:00:00

abstract：BACKGROUND:With the goal of reducing exposure to secondhand smoke, the state of Minnesota (MN), enacted a smoke-free law (i.e., Freedom to Breathe Act) in all workplaces, restaurants, and bars in 2007. This retrospective cohort study analyzes emergency department (ED) visits in Olmsted County, MN, for chronic obstructi...

journal_title：BMC pulmonary medicine

authors： Croghan IT,Ebbert JO,Hays JT,Schroeder DR,Chamberlain AM,Roger VL,Hurt RD

更新日期：2015-01-22 00:00:00

abstract：BACKGROUND:A variety of large randomized controlled trials (RCT's) evaluating pharmacotherapy in chronic obstructive pulmonary disease (COPD) patients does exist. One of the drugs that has been tested is the new long-acting anticholinergic glycopyrronium bromide. METHODS:As the generalizability of results from RCT's i...

journal_title：BMC pulmonary medicine

authors： Kardos P,Vogelmeier C,Buhl R,Criée CP,Worth H

更新日期：2015-01-12 00:00:00

abstract：BACKGROUND:We have previously shown that diabetic rats are more susceptible to sepsis, but that the Acute lung injury (ALI) secondary to sepsis is less intense than in non-diabetics. In the present study, we further investigated the ALI-secondary to sepsis in diabetic rats and the effect of insulin treatment. METHODS:...

journal_title：BMC pulmonary medicine

authors： Filgueiras LR,Capelozzi VL,Martins JO,Jancar S

更新日期：2014-11-15 00:00:00

abstract：BACKGROUND:Epithelial-mesenchymal transition (EMT) has been believed to be related with chemotherapy resistance in non-small cell lung cancer (NSCLC). Recent studies have suggested eIF5A-2 may function as a proliferation-related oncogene in tumorigenic processes. METHODS:We used cell viability assays, western blotting...

journal_title：BMC pulmonary medicine

authors： Xu G,Yu H,Shi X,Sun L,Zhou Q,Zheng D,Shi H,Li N,Zhang X,Shao G

更新日期：2014-11-07 00:00:00

abstract：BACKGROUND:Little is known about whether or how supplemental oxygen affects patients with pulmonary fibrosis. METHODS/DESIGN:A mixed-methods study is described. Patients with pulmonary fibrosis, informal caregivers of pulmonary fibrosis patients and practitioners who prescribe supplemental oxygen will be interviewed t...

journal_title：BMC pulmonary medicine

authors： Belkin A,Fier K,Albright K,Baird S,Crowe B,Eres L,Korn M,Maginn L,McCormick M,Root ED,Vierzba T,Wamboldt FS,Swigris JJ

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Activins are members of the TGF-ß superfamily of growth factors. First, we identified by expression array screening that activin-B and follistatin are upregulated in human idiopathic pulmonary fibrosis (IPF). Next, we wanted to clarify their specific role in lung fibrosis formation. METHODS:We used specific...

journal_title：BMC pulmonary medicine

authors： Myllärniemi M,Tikkanen J,Hulmi JJ,Pasternack A,Sutinen E,Rönty M,Leppäranta O,Ma H,Ritvos O,Koli K

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:The 2013 GOLD classification system for COPD distinguishes four stages: A (low symptoms, low exacerbation risk), B (high symptoms, low risk), C (low symptoms, high risk) and D (high symptoms, high risk). Assessment of risk is based on exacerbation history and airflow obstruction, whatever results in a higher...

journal_title：BMC pulmonary medicine

authors： Goossens LM,Leimer I,Metzdorf N,Becker K,Rutten-van Mölken MP

更新日期：2014-10-18 00:00:00

abstract：BACKGROUND:Asthma is a chronic inflammatory airway disease characterized by reversible obstruction, inflammation and hyperresponsiveness to different stimulus. Aerobic and breathing exercises have been demonstrated to benefit asthmatic patients; however, there is no evidence comparing the effectiveness of these treatme...

journal_title：BMC pulmonary medicine

authors： Evaristo KB,Saccomani MG,Martins MA,Cukier A,Stelmach R,Rodrigues MR,Santaella DF,Carvalho CR

更新日期：2014-10-17 00:00:00

abstract：BACKGROUND:Exposure to perinatal anxiety affects disease susceptibility in offspring but studies on the association between perinatal anxiety and gene polymorphisms are lacking. This study aimed to elucidate the interaction between perinatal anxiety and polymorphisms in antioxidant defense and innate immunity genes on ...

journal_title：BMC pulmonary medicine

authors： Lee E,Chang HY,Lee KS,Suh DI,Yu HS,Kang MJ,Choi IA,Park J,Kim KW,Shin YH,Ahn KM,Kwon JY,Choi SJ,Lee KJ,Won HS,Yang SI,Jung YH,Kim HY,Seo JH,Kwon JW,Kim BJ,Kim HB,Lee SY,Kim EJ,Lee JS,Keyes KM,Shin YJ,

更新日期：2014-09-29 00:00:00

abstract：BACKGROUND:Idiopathic pulmonary fibrosis (IPF) is a distinct form of interstitial pneumonia with unknown origin and poor prognosis. Current pharmacologic treatments are limited and lung transplantation is a viable option for appropriate patients. The aim of this review was to summarize lung transplantation survival in ...

journal_title：BMC pulmonary medicine

authors： Kistler KD,Nalysnyk L,Rotella P,Esser D

更新日期：2014-08-16 00:00:00

abstract：BACKGROUND:It is widely recognized that health-related quality of life (HRQL) is impaired in patients with Chronic Obstructive Pulmonary Disease (COPD), but there is a lack of research on longitudinal associations of COPD and HRQL. This study examined the effects of COPD in early stages of disease on HRQL over ten year...

journal_title：BMC pulmonary medicine

authors： Wacker ME,Hunger M,Karrasch S,Heinrich J,Peters A,Schulz H,Holle R

更新日期：2014-08-09 00:00:00

abstract：BACKGROUND:Air pollution has many negative health effects on the general population, especially children, subjects with underlying chronic disease and the elderly. The aims of this study were to evaluate the effects of traffic-related pollution on the exacerbation of asthma and development of respiratory infections in ...

journal_title：BMC pulmonary medicine

authors： Esposito S,Galeone C,Lelii M,Longhi B,Ascolese B,Senatore L,Prada E,Montinaro V,Malerba S,Patria MF,Principi N

更新日期：2014-08-07 00:00:00

abstract：BACKGROUND:The effectiveness of clinic-based pulmonary rehabilitation in advanced COPD is well established, but few data exist for less severe patients treated in alternative settings. The purpose of this study was to investigate whether a novel, community-based exercise program (CBE) was feasible and effective for pat...

journal_title：BMC pulmonary medicine

authors： Amin S,Abrazado M,Quinn M,Storer TW,Tseng CH,Cooper CB

更新日期：2014-08-04 00:00:00

abstract：BACKGROUND:Eotaxin proteins are a potential therapeutic target in treating the peribronchial eosinophilia associated with allergic airway diseases. Since inflammation is often associated with an increased generation of reactive oxygen species (ROS), oxidative stress is a mechanistically imperative factor in asthma. Ast...

journal_title：BMC pulmonary medicine

authors： Cho IH,Gong JH,Kang MK,Lee EJ,Park JH,Park SJ,Kang YH

更新日期：2014-07-29 00:00:00

abstract：BACKGROUND:Systemic inflammation plays an important role in the initiation, promotion, and progression of lung carcinogenesis. In patients with non-small cell lung cancer (NSCLC), fibrinogen levels correlate with neoplasia. Here we compared the effects of pulmonary rehabilitation (PR) with chest physical therapy (CPT) ...

journal_title：BMC pulmonary medicine

authors： Morano MT,Mesquita R,Da Silva GP,Araújo AS,Pinto JM,Neto AG,Viana CM,De Moraes Filho MO,Pereira ED

更新日期：2014-07-28 00:00:00

abstract：BACKGROUND:The pathological appearance of idiopathic pleuroparenchymal fibroelastosis (IPPFE) with hematoxylin-eosin staining is similar to that of usual interstitial pneumonia (UIP) in patients with idiopathic pulmonary fibrosis (IPF). The amount of elastic fibers (EF) and detailed differences between IPPFE and IPF ha...

journal_title：BMC pulmonary medicine

authors： Enomoto N,Kusagaya H,Oyama Y,Kono M,Kaida Y,Kuroishi S,Hashimoto D,Fujisawa T,Yokomura K,Inui N,Nakamura Y,Suda T

更新日期：2014-05-28 00:00:00

abstract：BACKGROUND:A recent method determines regional gas flow of the lung by electrical impedance tomography (EIT). The aim of this study is to show the applicability of this method in a porcine model of mechanical ventilation in healthy and diseased lungs. Our primary hypothesis is that global gas flow measured by EIT can b...

journal_title：BMC pulmonary medicine

authors： Bodenstein M,Boehme S,Bierschock S,Vogt A,David M,Markstaller K

更新日期：2014-04-29 00:00:00

abstract：BACKGROUND:Exercise capacity is impaired in pulmonary arterial hypertension (PAH). We hypothesized that cardiovascular reserve abnormalities would be associated with impaired hemodynamic response to pharmacological stress and worse outcome in PAH. METHODS:Eighteen PAH patients (p) group 1 NYHA class II/III and ten con...

journal_title：BMC pulmonary medicine

authors： Domingo E,Grignola JC,Aguilar R,Arredondo C,Bouteldja N,Messeguer ML,Roman A

更新日期：2014-04-24 00:00:00

abstract：BACKGROUND:Technology offers opportunities to improve healthcare, but little is known about Internet use by COPD patients. We tested two hypotheses: Internet access is associated with socio-demographic disparities and frequency of use is related to perceived needs. METHODS:We analyzed data from a 2007-2008 national co...

journal_title：BMC pulmonary medicine

authors： Martinez CH,St Jean BL,Plauschinat CA,Rogers B,Beresford J,Martinez FJ,Richardson CR,Han MK

更新日期：2014-04-22 00:00:00

abstract：BACKGROUND:Selection bias is a systematic error in epidemiologic studies that may seriously distort true measures of associations between exposure and disease. Observational studies are highly susceptible to selection bias, and researchers should therefore always examine to what extent selection bias may be present in ...

journal_title：BMC pulmonary medicine

authors： Johannessen A,Verlato G,Benediktsdottir B,Forsberg B,Franklin K,Gislason T,Holm M,Janson C,Jögi R,Lindberg E,Macsali F,Omenaas E,Real FG,Saure EW,Schlünssen V,Sigsgaard T,Skorge TD,Svanes C,Torén K,Waatevik M,Nils

更新日期：2014-04-16 00:00:00

abstract：BACKGROUND:Many studies have investigated whether pleural cholesterol levels can aid in diagnosis of pleural exudates, and the results have varied considerably. To gain a more reliable answer to this question, we meta-analyzed the literature on using pleural cholesterol or the ratio of cholesterol in pleural fluid to c...

journal_title：BMC pulmonary medicine

authors： Shen Y,Zhu H,Wan C,Chen L,Wang T,Yang T,Wen F

更新日期：2014-04-15 00:00:00

abstract：BACKGROUND:The accuracy of currently available same-day diagnostic tools (smear microscopy and conventional nucleic acid amplification tests) for pleural tuberculosis (TB) is sub-optimal. Newer technologies may offer improved detection. METHODS:Smear-microscopy, adenosine deaminase (ADA), interferon gamma (IFN-γ), and...

journal_title：BMC pulmonary medicine

authors： Meldau R,Peter J,Theron G,Calligaro G,Allwood B,Symons G,Khalfey H,Ntombenhle G,Govender U,Binder A,van Zyl-Smit R,Dheda K

更新日期：2014-04-08 00:00:00

abstract：BACKGROUND:In Europe, administration of an inhaled corticosteroid (ICS) combined with a long-acting β2 agonist is approved in chronic obstructive pulmonary disease (COPD) patients with a pre-bronchodilator FEV1 < 60% predicted normal, a history of repeated exacerbations, and who have significant symptoms despite regula...

journal_title：BMC pulmonary medicine

authors： Roche N,Pribil C,Van Ganse E,Serrier P,Housset B,Poirier D,Texier N,Schück S,Boucot I

更新日期：2014-04-02 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) exacerbations are accompanied with increased systemic inflammation, which accelerate the pulmonary function injury and impair the quality of life. Prompt and effective treatments for COPD exacerbations slow down the disease progression, but an objective instrument...

journal_title：BMC pulmonary medicine

authors： Tu YH,Zhang Y,Fei GH

更新日期：2014-03-11 00:00:00